“Jacob placed no qualifiers when he said the Savior would suffer ‘the pains of every living creature, both men, women and children, who belong to the family of .’ These were pains both related and unrelated to sin or transgression. In other words, the Savior voluntarily took upon himself not only the cumulative burden of sin and transgression, but also the cumulative burden of all depression, all loneliness, all sorrow, all mental, emotional, and physical hurt, and all weakness of every kind that afflicts mankind.”

Source: The Infinite Atonement